Restylane is one of the world’s first and foremost HA(Hyaluronic acid) dermal filler. Restylane is safe and is considered a natural cosmetics dermal filler because it is made of HA, a substance that exists in your body. You can smooth away unwanted wrinkles, restore natural contours of the face, and results in greater fullness to the skin. The effects are immediate and usually last 6-9 months.